Leucine is the main amino acid due to it's muscle building benefits.* This is the primary ingredient in the various ratio counts on the market, 2:1:1. 4:1:1, 8:1:1, 10:1:1, and 12:1:1. It is important to focus on how Leucine affects the body and the way it helps our muscles grow.* Leucine activates the protein known as mTOR, or Mechanistic target of rapamycin. It combines with other protein cells and begins to regulate cell growth.
Because of the importance of Leucine, many companies will stack more of it in the ratio for marketing . . . the more the better right?? You want that Leucine to instigate the protein synthesis process to put on more muscle . . .
Well sometimes more isn’t always better. A study was done where subjects were given Leucine, 2:1:1 BCAAs, and a placebo. The Reults found that BCAAs increased protein synthesis even more-so than Leucine alone. The study gave credit that BCAAs help to lessen fatigue and fuel muscles.*
People often see the higher number and figure 10:1:1 is five times better than 2:1:1 ratio . . . Here is the issue . . . There isn't much research supporting that the higher dosages will deliver any better results than a 2:1:1 ratio. So while you are paying more for a higher dosage, you may be flushing your money down the toilet. There is consistent studies and mention of the 2:1:1 ratio for more than 20 years. If you are serious about fitnes . . . stick with the tried and true, with plenty of research to support it.*